Last Updated on 6 May 2025 by Brisbane Livewell Clinic
Brisbane Livewell Clinic provides comprehensive Genetic Methylation Testing, helping our patients to achieve optimal health through personalised approaches based on their own genetic methylation profile.
This guide aims to provide a comprehensive overview of what a genetic methylation test is, how it works, and why it could be a vital tool for your health management, particularly through the services offered at Brisbane Livewell Clinic.
Why Methylation Matters for Your Health
Methylation is a core biochemical process that affects how every cell in your body functions. It influences how genes are switched on or off, how efficiently you produce energy, and how your body responds to environmental stressors.
Efficient methylation supports:
Brain and nervous system function
Detoxification pathways in the liver
Hormonal regulation and menstrual health
Mental clarity and emotional balance
Cardiovascular function and inflammation control
DNA repair and cellular ageing
When methylation is inefficient due to genetic variations or nutrient depletion, symptoms may show up as fatigue, mood changes, hormone issues, poor stress response, or increased sensitivity to environmental chemicals.
A genetic methylation test examines the methylation patterns in your DNA. Methylation is an epigenetic mechanism that involves adding a methyl group to the DNA molecule, affecting gene expression without altering the underlying genetic sequence. This process plays a crucial role in regulating gene activity, cellular function, and overall health.
Methylation is essential because it controls gene expression, turning genes on or off as needed. Proper methylation is vital for:
- Development and growth: Ensuring genes required for development are activated at the right times.
- Disease prevention: Silencing genes that could contribute to diseases if expressed inappropriately.
- Aging and longevity: Influencing the aging process and associated conditions.
Understanding your methylation patterns through a genetic methylation test at Brisbane Livewell Clinic can offer numerous benefits, including:
- Personalised health insights: Tailored recommendations for diet, lifestyle, and supplements based on your unique genetic profile.
- Early disease detection: Identifying potential health risks before symptoms appear.
- Optimised health management: We tailor your Comprehensive Health Report results and give you a Wellness Plan with our recommendations to improve your overall well-being.
Is This Type of Testing Relevant for You?
Genetic Methylation Testing may be worth considering if you:
Experience long-term fatigue, stress sensitivity or brain fog
Have a history of hormone imbalance, PMS or irregular cycles
React strongly to supplements or medications
Have a family history of MTHFR or similar gene variants
Want to better understand how your body responds to nutrients and stress
It’s also relevant for people interested in preventative health or looking for a deeper understanding of their biochemistry to inform dietary and supplement choices.
What Genes Are Analysed in a Methylation Test
Genetic Methylation Testing looks at variations in specific genes that influence how well your body can complete the methylation cycle. This includes well-known genes such as MTHFR, COMT, MTR, MTRR, BHMT and CBS. Each plays a different role in how the body processes nutrients, makes neurotransmitters, regulates hormones, clears toxins, and more.
For example, variations in the MTHFR gene may impact how your body converts folate into its active form. COMT is involved in breaking down stress hormones and certain neurotransmitters. By identifying where these genes may be underfunctioning or overactive, you and your Naturopath can understand how your body might be managing core functions like mood, energy and detoxification.
The Science Behind Methylation
Epigenetics and Gene Expression
Epigenetics refers to changes in gene activity that do not involve alterations to the genetic code itself. Methylation is a primary epigenetic mechanism, affecting how genes are expressed and regulated.
Factors Influencing Methylation
Several factors can influence methylation patterns, including:
- Diet: Nutrient intake can impact methylation. For instance, folate and vitamin B12 are crucial for proper methylation.
- Environment: Exposure to toxins and pollutants can affect methylation.
- Lifestyle: Stress, physical activity, and sleep can also influence methylation patterns.
What You’ll Learn from Your Results
This test provides insights into how your body manages the methylation cycle and related pathways. Rather than diagnosing conditions, the results highlight patterns that may contribute to symptoms you’re experiencing.
Your report will typically include:
A breakdown of relevant genetic variants
A functional overview of how your body processes folate, B12, and other key nutrients
Areas of strength and areas needing support
Nutritional and lifestyle suggestions that support healthy methylation
Interpreting your results in the context of your current symptoms and health goals allows for a focused, personalised approach to improving how you feel.
How Does a Genetic Methylation Test Work?
Testing is simple and non-invasive. A saliva sample is collected using a home test kit and returned to the laboratory for analysis. The results are reviewed in detail by your Naturopath, alongside your symptom picture and health history.
Once your results are received:
Your Naturopath will explain the key findings
They will interpret how the gene variants may be impacting your health
You’ll receive tailored recommendations for supporting your methylation function using nutrients, food and lifestyle strategies
1. Naturopath Consultation
The process at Brisbane Livewell Clinic with a consultation with one of our skilled and empathetic Practitioners. They will take a full history and discuss your health challenges, then recommend (or agree with you) that you take a Genetic Methylation DNA Test.
You will pay for your Genetic Methylation Test at our Reception counter, and we will order the kit to be sent to you. It may take a week or so for you to receive it.
2. Receive a Test Kit and Take a Sample
The DNA Test Kit will be posted to your home address (or other specified address). Just follow the simple instructions in the Test Kit and take a DNA swab from your saliva.
The swab can then be packed up and you can post it (within its pre-paid postage) back to NutriPath. They will then send it to the myDNA laboratory for analysis.
3. Laboratory Analysis
In the lab, scientists analyse the DNA sample to identify methylation patterns. Advanced technologies, such as next-generation sequencing, are used to provide accurate and detailed results.
4. Report Generation
After analysis, a Comprehensive Health Report is generated by myDNA, highlighting your methylation status, potential health risks, and some recommendations from myDNA. This Report will be sent to us at Brisbane Livewell Clinic, and we’ll arrange for you to come in and discuss your Comprehensive Health Report with our Naturopath.
5. myDNA Health Report and Wellness Plan Consultation
At your Naturopath Consultation, your Naturopath will discuss your Comprehensive Health Report with you and will make tailored recommendations about your health based on what is in the Report. They will work with you to develop a personalised Wellness Plan which sets out a plan of action – broken into steps – for improving your health and helping you to overcome your health challenges, which may include changes to your diet, lifestyle, and health management.
Your Naturopath may also recommend a course of supplements or liquid herbs to help your health improve.
Who Should Consider Getting a Genetic Methylation Test?
Genetic methylation testing can be beneficial for various people, including:
- Those with a family history of chronic diseases: To understand inherited risks and take preventive measures.
- Patients interested in personalised medicine: For tailored health and Wellness Plans from our Naturopaths.
- Anyone looking to optimise their health: To get a detailed understanding of their genetic makeup and improve lifestyle choices.
Benefits according to Nutripath:
- One test, with your unique DNA results, that lasts a lifetime.
- Helps to get to the root of health concerns.
- Identifies ways to be proactive in optimising your health and wellness.
- A tailored management plan, based on your unique DNA, to maximise health outcomes.B
Informed Consent
We recommend that you ensure you understand and agree to the terms of the DNA test, including how your genetic data will be used and protected. Make sure to discuss this with your health insurance provider, to determine whether there may be any impact.
Below are the statements made by both myDNA and NutriPath, our DNA Test providers/suppliers, in relation to your data security. We cannot guarantee the accuracy of these statements, so please do your own research, particularly into whether you will be required to disclose your DNA Test results to your health insurance fund.
Common Findings in Genetic Methylation Tests
Hypermethylation
Hypermethylation refers to excessive methylation, which can silence genes that should be active, potentially leading to health issues.
Hypomethylation
Hypomethylation indicates insufficient methylation, which can result in the activation of harmful genes.
Aberrant Methylation Patterns
Abnormal methylation patterns can be associated with various conditions, including cancer, cardiovascular diseases, and neurological disorders.
Common Misconceptions About Methylation and MTHFR
There are many myths circulating online about the impact of methylation variants like MTHFR. Having a variation does not necessarily mean your methylation is impaired or that you need high-dose supplements.
Your body has many ways to compensate for mild genetic differences, and lifestyle, nutrient status, stress, and gut health all influence whether these genes express. Methylation testing should always be interpreted in the context of your overall health, and not treated in isolation.
Working with a trained Naturopath ensures that your test results are understood in a balanced, clinically relevant way—so you can support your health without unnecessary worry or overtreatment.
Health Conditions Linked to Methylation
Cancer
Aberrant methylation patterns can contribute to the development and progression of cancer by silencing tumour suppressor genes or activating oncogenes.
Cardiovascular Diseases
Methylation can influence heart health by affecting genes involved in inflammation, cholesterol metabolism, and blood pressure regulation.
Neurological Disorders
Methylation patterns play a role in brain function and can be linked to conditions like Alzheimer’s disease, autism, and schizophrenia.
Latest Advances in Genetic Methylation Testing
Improved Technologies
Advancements in sequencing technologies have made methylation testing more accurate, accessible, and affordable.
Expanded Applications
Researchers are exploring new applications for methylation testing, including its use in monitoring disease progression and response to treatment.
Integration with Other Genetic Tests
Combining methylation testing with other genetic tests can provide a more comprehensive understanding of an individual’s health.
Cost of Genetic Methylation Testing
Factors Influencing Cost
Genetic methylation testing cost can vary based on factors such as the provider, the comprehensiveness of the test, and the technologies used.
Insurance Coverage
Check if your health insurance policy covers genetic methylation testing and (if so) what the reimbursement policies are. Also make sure you check whether having a genetic methylation test will affect your premiums or coverage.
Preparing for Your Appointment
Questions to Ask Your Naturopath at Brisbane Livewell Clinic
Prepare a list of questions to ask your Naturopath about the DNA test, its benefits, and its implications for your health.
What to Expect During the Test
Understand what to expect during the sample collection process and how to prepare for it.
Timing
Ask how long various steps are likely to take. For example:
1. Postage of the Genetic Methylation Test Kit to you (approximately 1 week)
2. Analysis of the DNA sample to identify methylation patterns (approximately 5-6 weeks at myDNA)
3. Return of your Comprehensive Health Report to Brisbane Livewell Clinic (approximately 1 week).
We suggest our patients allow 6 to 8 weeks for the whole process.
Follow-Up Appointments
Plan for follow-up appointments to discuss your test results with our Naturopath and next steps.
Top Tips for DNA Tests
- Choose a Reputable Provider: Ensure the provider is certified and uses reliable technologies, like myDNA through Brisbane Livewell Clinic.
- Understand the Purpose: Clarify why you need the test – for health risks, ancestry, or other reasons. The Genetic Methylation Test is only for health reasons.
- Consult a Professional: Before and after the test, consult with your Naturopaths to interpret the results accurately.
- Consider Privacy: Ensure your data will be protected and used ethically.
- Prepare Questions: Have a list of questions ready for your Naturopath regarding the test and results.
- Stay Informed: Keep up with the latest research and advances in genetic testing.
- Understand the Limitations: Know what the test can and cannot tell you about your health.
- Look at Family History: Consider how your family history might influence your test results.
- Use Results Wisely: Implement lifestyle and health changes based on your results.
- Follow Up: Schedule follow-up appointments with your Naturopath to discuss your progress and any new insights.
Conclusion
A genetic methylation test is a powerful tool for understanding your genetic makeup and taking proactive steps to manage your health. New advances in this field offer more accurate, accessible, and personalised insights than ever before. By understanding your methylation patterns with the expert guidance of the Naturopaths at Brisbane Livewell Clinic, you can make informed decisions about your health and well-being, potentially preventing chronic diseases and enhancing your quality of life.
For anyone considering a genetic methylation test, it’s essential to consult with a healthcare provider, choose a reputable testing provider like Brisbane Livewell Clinic (through myDNA), and understand the implications of the results by consulting with our skilled Naturopaths.
Frequently Asked Questions
1. What is a genetic methylation test?
A genetic methylation test examines the methylation patterns in your DNA, providing insights into gene expression and potential health risks. Brisbane Livewell Clinic (through myDNA) offers this advanced testing to help understand and manage your health better.
2. How is a genetic methylation test performed?
The test typically involves collecting a saliva sample at your home with the test kit (posted to you), which is then analysed in a lab to detect methylation patterns.
3. Who should consider getting a genetic methylation test?
Patients with a family history of chronic diseases, those interested in personalised medicine, and anyone looking to optimise their health and the health of their families should consider this test, available through our Naturopaths at Brisbane Livewell Clinic.
4. What can I learn from a genetic methylation test?
You can learn about your genetic predispositions, potential health risks, and receive personalised recommendations for diet, lifestyle, and health management from our expert Naturopaths at Brisbane Livewell Clinic.
5. How much does a genetic methylation test cost?
The cost of our Genetic Methylation Test Package at Brisbane Livewell Clinic, which includes 2 Naturopath consultations, your DNA test kit, your Comprehensive Health Report, and a tailored Wellness Plan, is $756.
6. Is genetic methylation testing covered by insurance?
Some insurance plans may cover genetic methylation testing. Check with your health care fund provider for specific coverage details.
Learn More About DNA Health Testing with Methylation
